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Sensitive RNase A detection and intracellular imaging using a natural compound-assisted tetrahedral DNA nanoprobe.
- Source :
-
Chemical Communications . 3/14/2020, Vol. 56 Issue 21, p3229-3232. 4p. - Publication Year :
- 2020
-
Abstract
- We report an intracellular imaging and assay nanoplatform for RNase A using a DNA tetrahedron-based fluorescent probe as a substrate. Importantly, a natural compound was used as an RNase A activity stimulator to improve the sensitivity. This platform provides an alternative for the diagnosis and prognosis of RNase A-related diseases and drug screening. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RIBONUCLEASE A
*DNA
*FLUORESCENT probes
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 56
- Issue :
- 21
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 142203062
- Full Text :
- https://doi.org/10.1039/d0cc00284d