Triethanolamine lactate-supported nanomagnetic cellulose: a green and efficient catalyst for the synthesis of pyrazolo[3,4-b]quinolines and theoretical study.

A novel nanomagnetic catalyst has been synthesized by immobilization of triethanolamine lactate cellulose with Fe3O4 NPs. The prepared catalyst has been used as an efficient and recoverable catalyst for the regioselective synthesis of pyrazolo quinolones by the three-component reaction of dimedone, 5-amino pyrazolone and aromatic aldehydes in ultrasound condition. This economical catalyst provides high yields of products, short experimental time and easy workup for green synthesis of pyrazolo[3,4-b]quinolone compounds. Theoretical studies have been employed to investigate the reaction mechanism by using the B3LYP/6-311G method. Electronic parameters of all components have been determined in order to reorganize the role of components in the reaction mechanism. [ABSTRACT FROM AUTHOR]