Cardiac Cell Therapy Rejuvenates the Infarcted Rodent Heart via Direct Injection but Not by Vascular Infusion.

Keywords: cell- and tissue-based therapy; models, animal; myocardial infarction; stem cells; translational research EN cell- and tissue-based therapy models, animal myocardial infarction stem cells translational research 1037 1039 3 04/20/20 20200324 NES 200324 Cardiac cell therapy using adult cells with stem- or progenitor-like properties has been under clinical investigation for more than 15 years. MNCs were largely absent from all tissues examined, including heart and lung (Figure, C), accounting for less than 3 cells per milligram tissue weight, or roughly 450 MNCs in an entire mouse heart. [Extracted from the article]