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Steroidal Components from the Roots and Rhizomes of Smilacina henryi and Their Cytotoxic Activities.

Authors :
Zhenlin Chen
Xuanji Xue
Shuo Zhang
Rongxin Zhang
Xiulei Zhang
Zengjun Guo
Xin Zhang
Source :
Records of Natural Products. May/Jun2020, Vol. 14 Issue 3, p225-230. 6p.
Publication Year :
2020

Abstract

Nine steroidal components, including a new pregnane glycoside (1), were obtained from the roots and rhizomes of Smilacina henryi. Their structures were determined via extensive spectroscopic data including, IR, HRESIMS and 1D, 2D NMR data analysis. Furthermore, their cytotoxic activities against human HepG2 and SW620 tumor cells were evaluated by the MTT method and compounds 2, 3, 5, 8 and 9 showed moderate activity with IC50 values raging from 18.4 to 86.3 μM. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13076167
Volume :
14
Issue :
3
Database :
Academic Search Index
Journal :
Records of Natural Products
Publication Type :
Academic Journal
Accession number :
142960691
Full Text :
https://doi.org/10.25135/rnp.156.1908.1390