Back to Search
Start Over
[3 + 3] Cycloaddition of aza-oxyallyl cations with 1,4-dithiane-2,5-diols for the construction of 3-thiomorpholinones.
- Source :
-
Synthetic Communications . 2020, Vol. 50 Issue 9, p1375-1387. 13p. 5 Diagrams, 3 Charts. - Publication Year :
- 2020
-
Abstract
- Base-mediated [3 + 3] cycloaddition reaction of in-situ formed aza-oxyallyl cations and 1,4-dithiane-2,5-diols has been achieved under mild reaction conditions. This strategy provides direct and efficient access to prepare desired thiomorpholin-3-one derivatives in moderate-to-high yields. The approach features broad substrates scope and short reaction time. Moreover, the resulting products can be readily converted into other useful heterocyclic compounds including 2H-1,4-thiazin-3(4H)-ones and thiomorpholine-3,5-diones. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RING formation (Chemistry)
*CATIONS
*HETEROCYCLIC compounds
*GLYCOLS
*CONSTRUCTION
Subjects
Details
- Language :
- English
- ISSN :
- 00397911
- Volume :
- 50
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Synthetic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 143137861
- Full Text :
- https://doi.org/10.1080/00397911.2020.1740738