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Identification of new arylsulfide derivatives as anti-melanogenic agents in a zebrafish model.
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Jul2020, Vol. 30 Issue 13, pN.PAG-N.PAG. 1p. - Publication Year :
- 2020
-
Abstract
- A series of aryl sulfide derivatives was synthesized and evaluated for their anti-melanogenic activities. Several compounds, including 3e , 3i and 3q exhibited good anti-melanogenic activities. Among the derivatives, compound 3i showed good inhibitory effects against melanin synthesis and showed no toxicity in reconstituted human eye and skin tissues. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MELANOGENESIS
*MELANINS
*IDENTIFICATION
*SKIN
Subjects
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 30
- Issue :
- 13
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 143248047
- Full Text :
- https://doi.org/10.1016/j.bmcl.2020.127201