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Noninvasive Estimation of Plasma Sodium Concentration During Hemodialysis via Capacitively Coupled Electrical Impedance Spectroscopy.
- Source :
-
IEEE Transactions on Instrumentation & Measurement . Apr2020, Vol. 69 Issue 4, p1673-1681. 9p. - Publication Year :
- 2020
-
Abstract
- This paper presents a compact, low-cost, and noninvasive system for real-time estimation of plasma sodium concentration ([Na] $_{Pl}$) during a hemodialysis (HD) session with state-of-the-art accuracy. It is based on the electrical impedance spectroscopy (EIS) performed with a capacitively coupled impedance sensing cell and a high-frequency measurement device, both custom-built. The EIS data are processed to infer the resistance of the liquid inside the cell, which is used together with an optical hemoglobin sensor to estimate the [Na] $_{\mathrm{Pl}}$. Validation of the EIS was performed by estimating the conductivity of the blood-mimicking fluid (BMF). The complete method was validated using the whole bovine blood, comparing the results to those obtained with standard instruments. The system was able to estimate the [Na] $_{\mathrm{Pl}}$ with sufficient accuracy (root-mean-square error (RMSE) of 3.0 mol/ $m^{3}$ with respect to reference data] to provide clinically useful information. The proof-of-concept hardware can be converted to a cheap and compact circuit board for integration into an HD machine. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00189456
- Volume :
- 69
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- IEEE Transactions on Instrumentation & Measurement
- Publication Type :
- Academic Journal
- Accession number :
- 143313542
- Full Text :
- https://doi.org/10.1109/TIM.2019.2913612