Prostaglandin D2 receptors in human mast cells.

Keywords: DP1; DP2 (CRTH2); mast cells; nasal polyps; prostaglandin D2 EN DP1 DP2 (CRTH2) mast cells nasal polyps prostaglandin D2 1477 1480 4 06/01/20 20200601 NES 200601 To the Editor, Mast cells are important effector cells playing a critical role in regulation of immune responses in allergic diseases. Altogether, neither LAD2 nor LUVA human mast cell lines were activated by PGD SB 2 sb despite high expression of DP2 detected in LUVA cells. Expression of DP2 (CRTH2) was measured on peripheral blood basophils (CD123+, FceRIa+) (A), mast cells from nasal polyps (c-kit+, Fc RIa+) (B), and mast cells from nasal turbinates (C) by flow cytometry. [Extracted from the article]