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On the modeling of HIV dynamics driven by cell-to-cell and virus-to-cell transmissions.
- Source :
-
Journal of Analysis & Applications . Sep2020, Vol. 18 Issue 2, p133-143. 11p. - Publication Year :
- 2020
-
Abstract
- In this paper, a model of HIV infection taking into account cell-free and cell-to-cell transmissions is investigated under latency. The viral production rate of infectious CD4 T cells and the activation rate of latently infected CD4 T cells play a major role in the evolution of the disease. A system of nonlinear differential equations is derived to capture the dynamics and systematically analyzed thanks to the spectral theory of dynamical systems and a Routh-Hurwitz criterion. In particular, numerical simulations will be performed in order to extract the critical epidemiological features of the solution. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09725954
- Volume :
- 18
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Analysis & Applications
- Publication Type :
- Academic Journal
- Accession number :
- 143515902