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NMDA receptor antagonists ameliorate the stepping deficits produced by unilateral medial forebrain bundle injections of 6-OHDA in rats.

Authors :
Kelsey, John E.
Mague, Stephen D.
Pijanowski, Reyna S.
Harris, Ryan C.
Kleckner, Nancy W.
Matthews, Russell T.
Source :
Psychopharmacology. 2004, Vol. 175 Issue 2, p179-188. 10p. 3 Charts, 6 Graphs.
Publication Year :
2004

Abstract

Provides information on a study which examined the effects of various NMDA receptor antagonists on a developed rat model of Parkinson's disease. Sensitive measure of akinesia in unilateral 6-OHDA-lesioned rats; Characteristics of the disease; Type of transmission associated with the disease.

Details

Language :
English
ISSN :
00333158
Volume :
175
Issue :
2
Database :
Academic Search Index
Journal :
Psychopharmacology
Publication Type :
Academic Journal
Accession number :
14353947
Full Text :
https://doi.org/10.1007/s00213-004-1799-5