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Sarcaglabrin A, a conjugate of C15 and C10 terpenes from the aerial parts of Sarcandra glabra.
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Jun2020, Vol. 61 Issue 25, pN.PAG-N.PAG. 1p. - Publication Year :
- 2020
-
Abstract
- • Investigation of a medicinal plant Sarcandra glabra gave sarcaglabrins A-C. • Their structures were assigned by spectroscopic analyses including ECD calculation. • Sarcaglabrin A was assigned as a new conjugate of C 15 and C 10 terpenes. A new C 25 terpene consisting of C 15 and C 10 terpenes, sarcaglabrin A, and two new sesquiterpene dimers, sarcaglabrins B and C, were isolated from the aerial parts of a medicinal plant Sarcandra glabra used in Guangxi Zhuang Autonomous Region, China. Their structures were elucidated on the basis of detailed spectroscopic analyses including calculation of the ECD spectrum. Sarcaglabrin A was assigned as a conjugate of lindenane type sesquiterpene and ocimene type monoterpene, while sarcaglabrins B and C were elucidated to be lindenane sesquiterpene dimers. Their cytotoxicity against human cancer cell lines were evaluated. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MEDICINAL plants
*CELL lines
*DIMERS
*CANCER cells
*TERPENES
Subjects
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 61
- Issue :
- 25
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 143551441
- Full Text :
- https://doi.org/10.1016/j.tetlet.2020.151916