A core outcome set for future endometriosis research: an international consensus development study.

<bold>Objective: </bold>To develop a core outcome set for endometriosis.<bold>Design: </bold>Consensus development study.<bold>Setting: </bold>International.<bold>Population: </bold>One hundred and sixteen healthcare professionals, 31 researchers and 206 patient representatives.<bold>Methods: </bold>Modified Delphi method and modified nominal group technique.<bold>Results: </bold>The final core outcome set includes three core outcomes for trials evaluating potential treatments for pain and other symptoms associated with endometriosis: overall pain; improvement in the most troublesome symptom; and quality of life. In addition, eight core outcomes for trials evaluating potential treatments for infertility associated with endometriosis were identified: viable intrauterine pregnancy confirmed by ultrasound; pregnancy loss, including ectopic pregnancy, miscarriage, stillbirth and termination of pregnancy; live birth; time to pregnancy leading to live birth; gestational age at delivery; birthweight; neonatal mortality; and major congenital abnormalities. Two core outcomes applicable to all trials were also identified: adverse events and patient satisfaction with treatment.<bold>Conclusions: </bold>Using robust consensus science methods, healthcare professionals, researchers and women with endometriosis have developed a core outcome set to standardise outcome selection, collection and reporting across future randomised controlled trials and systematic reviews evaluating potential treatments for endometriosis. TWEETABLE ABSTRACT: @coreoutcomes for future #endometriosis research have been developed @jamesmnduffy. [ABSTRACT FROM AUTHOR]