Skin insertion analysis of microneedle using ANSYS and fuzzy logic.

Computers have been used in different areas of medical technology and applications. Innovation in the field of tehnology has been considered as a fundamental consitutent of medical discipline. Advancement in the field of medical and health care results in an ease for disease diagnostic, reduction in risk of diseases and lessen pain which is eventually beneficial to human life. In this work, the designing and effect of skin puncturing of micro-needle was studied. The simulations for skin puncturing was performed in ANSYS and MATLAB fuzzy logic tool. The skin puncturing using needle based on human skin coatings including dermis, stratum corneum and viable epidermis was studied. Fuzzy logic analysis was use to study the effect of effect of applied stress and tip diameter of the needle on the three layers of skin. A 3D model of human skin layer and needle was created in ANSYS and studied for an applied force of 0.4 to 0.9 N. Thinner the tip diameter of the needle, more penetration and puncturing of skin will occur. Similarly, for applied skin, more stress is required for proper puncturing of stratum corneum layer of human skin. The microfluidic analysis performed in the CFX environment of ANSYS shows that at the driving pressure of 140 kPa, 415μL/min flow rate has been achieved. [ABSTRACT FROM AUTHOR]