早产原因相关研究热点的文献计量学分析.

Objective: To search the hotspots and research trend of premature birth by bibliometric analysis, so as to propose the new directions for further research. Methods：Studies about Premature Birth in PubMed were searched from the establishment to April 2019. Bibliographic Items Co-Occurrence Matrix Builder (BICOMB) was used to extract the retrieved documents. High-frequency MeSH terms were identified to form article Matrix and co-occurrence Matrix. Hierarchical cluster analysis was conducted by SPSS 20.0 to form the hotspots. The strategic diagram was then created. Results：A total of 2 965 papers were retrieved, and 3 183 main MeSH terms were extracted by BICOMB software. Sixty four high-frequency keywords were determined and divided into six relevant research hotspots. Finally, a strategic diagram reflecting the development trend of each research hotspot was formed. Conclusions：The pregnant complications and comorbidities, adverse outcomes of maternal and child caused by premature birth, maternal body mass index, gestational age and parity were well developed as the relevant research hotspots. On the contrary, the factors of society, psychologyand genetics, and the adverse exposure during pregnancy, were not adequately documented, suggesting that these factors could be studied in future. In addition, the researches on the diagnosis and prevention of preterm birth are relatively mature, but the connection with other studies is not close enough and further development is needed. [ABSTRACT FROM AUTHOR]