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Osteoporosis-related Vertebral Fragility Fractures: A Review and Analysis of the American Orthopaedic Association's Own the Bone Database.
- Source :
-
Spine (03622436) . 4/15/2020, Vol. 45 Issue 8, pE430-E438. 9p. - Publication Year :
- 2020
-
Abstract
- <bold>Study Design: </bold>Retrospective cohort study of the Own the Bone database which is a fracture liaison service designed to improve recognition and treatment of osteoporosis.<bold>Objective: </bold>To use the Own the Bone (OTB) database to 1) examine the specific demographics of patients presenting with a low-energy clinical vertebral fracture (VFX) and 2) compare demographic and fracture-specific risk factors between patients with clinical VFX versus patients with nonvertebral low-energy fracture (NVFX).<bold>Summary Of Background Data: </bold>Large database studies have described risk factors for developing VFX. It is well described that a history of previous VFX portends an increased risk of future VFX. Few studies have reported cohorts from a fracture liaison service such as the OTB initiative.<bold>Methods: </bold>35,039 unique cases of fragility fracture occurred between 2009 and 2016 and were included in analysis. VFX accounted for 3395 (9.9%) of the presenting fractures at OTB enrollment. The demographics, lifestyle factors, medication use, and fracture-specific data for patients in the OTB registry with vertebral fractures were summarized and then statistically compared to those with nonvertebral fragility fractures.<bold>Results: </bold>The majority of VFX patients were Caucasian, postmenopausal women (74.4%). There was an increased likelihood of presenting with a vertebral fracture in patients who sustained a previous VFX after the age of 50, while patients who sustained a prior nonvertebral fracture (NVFX) were more likely to present with a subsequent NVFX. After controlling for patients with a history of fracture after the age of 50, VFX patients (vs. NVFX) were more likely to be age 70-79, class 1 obesity, with a history of taking anti-osteoporotic prescription medications.<bold>Conclusions: </bold>Multiple factors were associated with a significantly increased risk of VFX compared with NVFX. Understanding the risk factors unique to fragility VFX is a critical component for targeting "at-risk" patients and preventing future osteoporosis-related fractures and their consequences.<bold>Level Of Evidence: </bold>4. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BONES
*POSTMENOPAUSE
*OSTEOPOROSIS
*MEDICAL registries
*DATABASES
*SERVICE design
Subjects
Details
- Language :
- English
- ISSN :
- 03622436
- Volume :
- 45
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Spine (03622436)
- Publication Type :
- Academic Journal
- Accession number :
- 143845886
- Full Text :
- https://doi.org/10.1097/BRS.0000000000003324