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Impact of cataract surgery on depression and cognitive function: Systematic review and meta‐analysis.
- Source :
-
Clinical & Experimental Ophthalmology . Jul2020, Vol. 48 Issue 5, p593-601. 9p. - Publication Year :
- 2020
-
Abstract
- Importance In elderly people, visual impairment is associated with depressive symptoms and cognitive decline. However, the impact of cataract surgery on depression and cognitive impairment is still controversial. Background: To evaluate the effect of cataract surgery on depression and cognitive status in the elderly. Design This study was a meta‐analysis. Participants: Patients with age‐related cataract who underwent cataract surgery were recruited for this study. Methods: A literature search was performed on PubMed, Scopus and Web of Science. Data were extracted from selected studies by two independent reviewers. The pooled standardized mean difference (SDM) was estimated using a random‐effects model. Heterogeneity was evaluated using the Q and I2 tests. Multiple sensitivity analyses and assessment of publication bias were performed. Main Outcome Measures: The main outcome was a report of a measure of depression or cognitive impairment before and after surgery. Results: Sixteen studies were included: 14 of them reported data on depression and 9 of them on cognitive function. Depression significantly decreased after surgery (SDM = 0.460; 95% CI: 0.223‐0.697; P <.001). In six controlled studies, the reduction of depression was higher in the surgery group than in the control group (SDM = 0.161; 95% CI: 0.027‐0.295; P =.019). Cognitive function significantly improved after surgery (SDM = 0.254; 95% CI: 0.120‐0.388; P <.001). In four controlled studies, the improvement of cognitive function was higher in the surgery group than in the control group (SDM = 0.188; 95% CI: 0.002‐0.374; P =.048). Results were stable after sensitivity analyses. Conclusions and Relevance: This meta‐analysis provides evidence that cataract surgery has a positive effect on depression and cognitive function in the elderly. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14426404
- Volume :
- 48
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Clinical & Experimental Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 144472319
- Full Text :
- https://doi.org/10.1111/ceo.13754