Cigarette smoking prior to blood sampling acutely affects serum levels of the chronic obstructive pulmonary disease biomarker surfactant protein D.

Keywords: biomarker; chronic obstructive pulmonary disease; cigarette smoking; preanalytical variability EN biomarker chronic obstructive pulmonary disease cigarette smoking preanalytical variability e138 e141 4 07/13/20 20200801 NES 200801 To the Editor, Biomarker tests in pulmonary medicine show great promise with regard to improving patient care, yet their translation into widely used clinical tests is a slow and rather ineffective process. In this study, we examined the acute effects of cigarette smoking on serum levels of surfactant protein D (SPD), which represents another promising and (predominantly) lung-derived COPD biomarker candidate. [Extracted from the article]