Assessing the effects of metropolitan-wide quarantine on the spread of COVID-19 in public space and households.

• A new dynamic compartmental model involving two modes of transmission (public space and households) is proposed to evaluate the impact of the metropolitan-wide quarantine on the trend and transmission pattern of the COVID-19 epidemic in Hubei, China. • The quarantine reduces more than 70% of new infections in both households and the public space, as well as the deaths caused by COVID-19 pneumonia. Household transmission is the dominant route of disease spread regardless of quarantine. • The results will provide important evidence and scientific insights to other worldwide countries that are currently under quarantine. Hubei province in China has completed cycle of quarantine-resumption in 23rd Janauary and 8th April 2020, providing a unique opportunity as for now to assess its intervention impact and the pattern of SARS-COV-2 transmission during the quarantine period. In this study, we evaluate the impact of the metropolitan-wide quarantine on the trend and transmission route of the COVID-19 epidemic in Hubei, China. The intervention reduces more than 70% of new infections in both households and the public space, as well as the deaths caused by COVID-19 pneumonia. Household transmission is the dominant route of disease spread regardless of quarantine. This will provide important evidence and scientific insights to other worldwide countries that are currently under quarantine. [ABSTRACT FROM AUTHOR]