Primary mediastinal large B‐cell lymphoma in paediatric and adolescent patients: emerging questions in the era of immunotherapy.

Primary mediastinal large B-cell lymphoma in paediatric and adolescent patients: emerging questions in the era of immunotherapy Keywords: paediatric; refractory; mediastinal; B-Cell lymphoma EN paediatric refractory mediastinal B-Cell lymphoma e114 e117 4 07/20/20 20200715 NES 200715 Relapsed/refractory primary mediastinal large B-cell lymphoma (PMLBCL) is rare among paediatric patients and is associated with a dismal prognosis. None of these patients had prior CAR T-cell therapy or checkpoint inhibitors.13 Remission consolidation post-CAR T-cell therapy with allogeneic HCT in patients with PMLBCL remains an active debate. [Extracted from the article]