Back to Search Start Over

Co-delivery of IKBKE siRNA and cabazitaxel by hybrid nanocomplex inhibits invasiveness and growth of triple-negative breast cancer.

Authors :
Zhen Zhao
Yuanke Li
Hao Liu
Jain, Akshay
Patel, Pratikkumar Vinodchandra
Kun Cheng
Source :
Science Advances. 7/15/2020, Vol. 6 Issue 29, p1-14. 14p.
Publication Year :
2020

Abstract

The article presents cancer research on Co-delivery of inhibitor of nuclear factor kappa‐B kinase subunit epsilon (IKBKE) siRNA and cabazitaxel by hybrid nanocomplex inhibits invasiveness and growth of triple-negative breast cancer. Topics including IKBKE small interfering RNA (siRNA) inhibits the proliferation, migration, and invasion of TNBC cells; and nanocomplex shows higher cellular uptake and better tumor penetration of the encapsulated cargos.

Details

Language :
English
ISSN :
23752548
Volume :
6
Issue :
29
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
144682856
Full Text :
https://doi.org/10.1126/sciadv.abb0616