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Recent Development in Applications of Synthetic Phenoxazines and Their Related Congeners: A Mini‐Review.

Authors :
Onoabedje, Efeturi A.
Ayogu, Jude I.
Odoh, Amaechi S.
Source :
ChemistrySelect. 7/31/2020, Vol. 5 Issue 28, p8540-8556. 17p.
Publication Year :
2020

Abstract

Phenoxazines have gained enormous interest because of their diverse applications in both material science and chemotherapy. They exhibit numerous biological activities, ranging from anti‐malarial, anticancer, antiviral, antidiabetic, anti‐Alzheimer, antioxidant, anti‐inflammatory, to antibiotic and many more. Actinomycin D, for instance, which embodies a phenoxazine scaffold, displays both antibiotic and anticancer property. Phenoxaxines have also found usefulness in organic light‐emitting diodes, fluorescent probes and dye‐sensitized solar cells. Over the years, various research groups have strived for several structural modifications targeting new derivatives of phenoxazines with improved properties. This present review highlights the progress, challenges and prospects in medicinal and material applications of phenoxazine moiety to provide greater insight into the development of future derivatives with improved properties. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23656549
Volume :
5
Issue :
28
Database :
Academic Search Index
Journal :
ChemistrySelect
Publication Type :
Academic Journal
Accession number :
144869529
Full Text :
https://doi.org/10.1002/slct.202001932