Tuesday June 1st, 2004 14:30-16:30 Hall E Discussion Group Current concepts and controversies in Rasmussen's encephalitis.

The article presents information about abstracts of various papers that will be discussed at the Discussion Group of the 6th European Congress on Epileptology that will be held on June 1, 2004. One of the papers that will be discussed is "Humoral Pathogenesis," by R. Mantegazza, P. Bernasconi and R. Spreafico. The autoimmune pathogenesis in Rasmussen's encephalitis (RE) has been proposed on the basis of the finding of antibodies against glutamate receptor 3 (GluR3) in patients' sera, and subsequently for their potential excitotoxic effect or killing activity on neuronal cells by a complement mediated mechanism. Other papers that will be discussed are "Cellular Pathogenesis," by C. Bien and "The Role of EEG and MRI," by T. Granata.