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Bioactive Alkaloids from Whole Plants of Thalictrum cultratum.

Authors :
Lv, Na
Luo, Dian
Zhu, Li-Jun
Xu, Yong
Wang, Jin
Kong, Wei-Song
Li, Jin
Gao, Qian
Mi, Qi-Li
Zhou, Min
Yang, Guang-Yu
Hu, Qiu-Fen
Huang, Hai-Tao
Source :
Chemistry of Natural Compounds. Jul2020, Vol. 56 Issue 4, p696-700. 5p.
Publication Year :
2020

Abstract

Two new tricyclic alkaloids (1 and 2), together with three known (3–5) alkaloids, were isolated from the whole plants of Thalictrum cultratum. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1–5 were tested for their anti-rotavirus activity. The results revealed that compounds 1–5 exhibited potent anti-rotavirus activity with therapeutic index (TI) values in the range 10.7–17.7. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*PLANTS

Details

Language :
English
ISSN :
00093130
Volume :
56
Issue :
4
Database :
Academic Search Index
Journal :
Chemistry of Natural Compounds
Publication Type :
Academic Journal
Accession number :
145047539
Full Text :
https://doi.org/10.1007/s10600-020-03122-y