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Association between periodontal disease, tooth loss and liver diseases risk.
- Source :
-
Journal of Clinical Periodontology . Sep2020, Vol. 47 Issue 9, p1053-1063. 11p. 1 Diagram, 5 Charts, 1 Graph. - Publication Year :
- 2020
-
Abstract
- Aim: The purpose of this study is to assess the associations between periodontal disease, tooth loss and liver diseases. Materials and methods: PubMed and Embase databases were utilized to search eligible studies. Odds ratio (OR) with 95% confidence interval (CI) was used as effect size to assess the associations between periodontal disease, tooth loss and liver diseases risk. Results: Our results indicated positive associations between periodontal disease and non‐alcoholic fatty liver disease (NAFLD) (OR = 1.19, 95% CI = 1.06–1.33), liver cirrhosis (OR = 2.28, 95% CI = 1.50–3.48) and elevated transaminase level risk (OR = 1.08, 95% CI = 1.02–1.15). Moreover, tooth loss could increase NAFLD (OR = 1.33, 95% CI = 1.12– 1.56) and liver cancer risk (OR = 1.34, 95% CI = 1.04–1.74), and every five increment in tooth loss was associated with 5% increased liver cancer risk (OR = 1.05, 95% CI = 1.01 – 1.10) with a linear relationship. In addition, tooth loss had a positive tendency towards liver cirrhosis risk (OR = 2.03, 95% CI = 0.85–4.85) although there was no statistical significance. Conclusion: Periodontal disease and tooth loss are positively associated with liver diseases including NAFLD, elevated transaminase level, liver cirrhosis and liver cancer. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03036979
- Volume :
- 47
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Journal of Clinical Periodontology
- Publication Type :
- Academic Journal
- Accession number :
- 145203612
- Full Text :
- https://doi.org/10.1111/jcpe.13341