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Efficient construction of a stable linear gene based on a TNA loop modified primer pair for gene delivery.
- Source :
-
Chemical Communications . 9/4/2020, Vol. 56 Issue 68, p9894-9897. 4p. - Publication Year :
- 2020
-
Abstract
- A terminal-closed linear gene with strong exonuclease resistance and serum stability was successfully constructed by polymerase chain reaction (PCR) with an α- L -threose nucleic acid (TNA) loop modified primer pair, which can be used as an efficient gene expression system in eukaryotic cells for gene delivery. [ABSTRACT FROM AUTHOR]
- Subjects :
- *POLYMERASE chain reaction
*EUKARYOTIC cells
*GENE expression
*GENES
*NUCLEIC acids
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 56
- Issue :
- 68
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 145300206
- Full Text :
- https://doi.org/10.1039/d0cc04356g