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Red light-triggered photoreduction on a nucleic acid template.

Authors :
Dutta, Subrata
Rühle, Jennifer
Schikora, Margot
Deussner-Helfmann, Nina
Heilemann, Mike
Zatsepin, Timofei
Duchstein, Patrick
Zahn, Dirk
Knör, Günther
Mokhir, Andriy
Source :
Chemical Communications. 9/7/2020, Vol. 56 Issue 69, p10026-10029. 4p.
Publication Year :
2020

Abstract

Conjugate Sn(IV)(pyropheophorbide a)dichloride–(peptide nucleic acid) catalyzes reduction of azobenzene derivatives in the presence of complementary nucleic acid (NA) upon irridiation with red light (660 nm). This is the first red light-induced NA-templated photoreduction. It is highly sensitive to single mismatches in the NA-template and can detect down to 5 nM NAs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
56
Issue :
69
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
145341026
Full Text :
https://doi.org/10.1039/d0cc03086d