Microstructure, corrosion resistance, osteogenic activity and antibacterial capability of Mn-incorporated TiO2 coating.

• The coating contains a Mn-rich outer layer and a polycrystalline inner layer. • Mn specie mainly exists as Mn 3 O 4. • The antibacterial capability is mainly ascribed to Mn 3 O 4. • Mn incorporation enhances cellular response and corrosion resistance of TiO 2. In the present work, a Mn-incorporated TiO 2 coating has been fabricated through the facile one-step micro-arc oxidation (MAO) treatment in the electrolyte containing Na 2 Mn-EDTA. Microstructural characterization reveals that Mn-incorporated TiO 2 coating exhibits a two-layered structure based on chemical compositions, which includes the inner layer consisting of polycrystalline TiO 2 with P segregated at the grain boundary and the outer layer comprising of nano-sized Mn 3 O 4 particles. Further, both corrosion resistance and biological performance of the Mn-incorporated TiO 2 coating were investigated. It was revealed that the Mn-incorporated TiO 2 coating exhibits an enhanced corrosion resistance, osteogenic activity and slightly improved antibacterial capability against S. aureus bacteria relative to that with the absence of Mn, which also exhibits negligible cytotoxicity. Hence, Mn specie is a promising candidate for the production of dual-functional biomedical surfaces for Ti implants. [ABSTRACT FROM AUTHOR]