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Recent advances in fluorescent probes for G-quadruplex nucleic acids.
- Source :
-
Biochemical & Biophysical Research Communications . Oct2020, Vol. 531 Issue 1, p18-24. 7p. - Publication Year :
- 2020
-
Abstract
- G-quadruplexes are non-canonical nucleic acid structures formed by guanine-rich DNA or RNA sequences. In recent decades, an increasing number of evidences have suggested that G-quadruplexes are associated with a wide range of biological events. Therefore, to further study the function and distribution of G-quadruplexes, developing new probes is an essential part of G-quadruplexes research. In the review, several examples of chemical fluorescent probes for G-quadruplexes developed in recent years are highlighted. These probes are promising tools for future G-quadruplex studies, which display outstanding selectivity and capability of cell imaging. • Chemical fluorescent probes are crucial tools for the research of G-quadruplexes. • The recently developed fluorescent probes for G-quadruplexes are highlighted. • The fluorescent probes are categorized by their different G-quadruplex targets. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 531
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 145474529
- Full Text :
- https://doi.org/10.1016/j.bbrc.2020.02.114