Back to Search
Start Over
Minicircle DNA: The Future for DNA-Based Vectors?
- Source :
-
Trends in Biotechnology . Oct2020, Vol. 38 Issue 10, p1047-1051. 5p. 1 Chart. - Publication Year :
- 2020
-
Abstract
- Minicircle DNA (mcDNA) is a smaller and safer version of non-viral DNA vectors that results from a cutting-edge in vivo recombination process to excise prokaryotic sequences from plasmid DNA (pDNA). Considering the molecule's potential and increasing interest as a non-viral DNA-based therapeutic, biomanufacturing methodologies need to be improved, especially in downstream processing. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DNA
*MOLECULES
Subjects
Details
- Language :
- English
- ISSN :
- 01677799
- Volume :
- 38
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Trends in Biotechnology
- Publication Type :
- Academic Journal
- Accession number :
- 145650869
- Full Text :
- https://doi.org/10.1016/j.tibtech.2020.04.008