Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine...

Authors :: Griffith, Eric C.
Su, Zhuang
Source :: Proceedings of the National Academy of Sciences of the United States of America. 12/22/98, Vol. 95 Issue 26, p15183. 6p. 3 Diagrams, 3 Graphs.
Publication Year :: 1998
Abstract: Presents information on a study which hypothesized that fumagillin and ovacilin inhibit type 2 methionine aminopeptidase (MetAP2) by irreversible blockage of the active site. Features of fumagillin and ovacilin; Materials and methods; Results from the synthesis of deoxyfumagillin analogs.

Language :: English
ISSN :: 00278424
Volume :: 95
Issue :: 26
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 1456608
Full Text :: https://doi.org/10.1073/pnas.95.26.15183

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