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Characterization and digestion features of a novel polysaccharide-Fe(III) complex as an iron supplement.
- Source :
-
Carbohydrate Polymers . Dec2020, Vol. 249, pN.PAG-N.PAG. 1p. - Publication Year :
- 2020
-
Abstract
- • A polysaccharide-Fe(III) complex, AGSP-Fe(III), was synthesized and characterized. • Fe release of AGSP-Fe(III) in simulated gastrointestinal digestion was exhibited. • Its iron supplementary efficiency was shown using Caco-2 cell model. • The solubility and stability of the complex were superior to FeCl 3. Using a sulfated polysaccharide from the gonad of pacific abalone (AGSP), a novel polysaccharide-Fe(III) complex, AGSP-Fe(III), was synthesized, and it was characterized by a series of methods including ultraviolet-visible (UV–vis) spectroscopy, Fourier transform-infrared (FT-IR) spectroscopy, circular dichroism (CD) spectroscopy, scanning electron microscopy (SEM), and atomic force microscopy (AFM). The results showed that AGSP-Fe(III) was formed by the Fe-O bond between sulfate, carboxyl, and hydroxyl groups in AGSP and Fe, its particle size reached a maximum of 200 nm after aggregating, and its surface morphology presented relatively regular columnar or spherical. Moreover, the iron release of AGSP-Fe(III) during simulated gastrointestinal digestion was exhibited, and its good iron supplementary efficiency was also shown using Caco-2 cells. In addition, compared to FeCl 3 , AGSP-Fe(III) showed better solubility and stability in the presence of polyphenol/trypsin. The present study demonstrated the potential of AGSP-Fe(III) as a novel iron supplement. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01448617
- Volume :
- 249
- Database :
- Academic Search Index
- Journal :
- Carbohydrate Polymers
- Publication Type :
- Academic Journal
- Accession number :
- 145738713
- Full Text :
- https://doi.org/10.1016/j.carbpol.2020.116812