Vesicular neurotransmitter transporters in Drosophila melanogaster.

Drosophila melanogaster express vesicular transporters for the storage of neurotransmitters acetylcholine, biogenic amines, GABA, and glutamate. The large array of powerful molecular-genetic tools available in Drosophila enhances the use of this model organism for studying transporter function and regulation. • Drosophila melanogaster express orthologs of mammalian vesicular transporters. • Drosophila also express some vesicular transporters not found in mammals. • Mutants and transgenes available in Drosophila can be used to study transporter function. [ABSTRACT FROM AUTHOR]