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Clinical Characteristics of Hospitalized Individuals Dying With COVID-19 by Age Group in Italy.
- Source :
-
Journals of Gerontology Series A: Biological Sciences & Medical Sciences . Sep2020, Vol. 75 Issue 9, p1796-1800. 5p. - Publication Year :
- 2020
-
Abstract
- <bold>Background: </bold>Aim of the present study is to describe characteristics of COVID-19-related deaths and to compare the clinical phenotype and course of COVID-19-related deaths occurring in adults (<65 years) and older adults (≥65 years).<bold>Method: </bold>Medical charts of 3,032 patients dying with COVID-19 in Italy (368 aged < 65 years and 2,664 aged ≥65 years) were revised to extract information on demographics, preexisting comorbidities, and in-hospital complications leading to death.<bold>Results: </bold>Older adults (≥65 years) presented with a higher number of comorbidities compared to those aged <65 years (3.3 ± 1.9 vs 2.5 ± 1.8, p < .001). Prevalence of ischemic heart disease, atrial fibrillation, heart failure, stroke, hypertension, dementia, COPD, and chronic renal failure was higher in older patients (≥65 years), while obesity, chronic liver disease, and HIV infection were more common in younger adults (<65 years); 10.9% of younger patients (<65 years) had no comorbidities, compared to 3.2% of older patients (≥65 years). The younger adults had a higher rate of non-respiratory complications than older patients, including acute renal failure (30.0% vs 20.6%), acute cardiac injury (13.5% vs 10.3%), and superinfections (30.9% vs 9.8%).<bold>Conclusions: </bold>Individuals dying with COVID-19 present with high levels of comorbidities, irrespective of age group, but a small proportion of deaths occur in healthy adults with no preexisting conditions. Non-respiratory complications are common, suggesting that the treatment of respiratory conditions needs to be combined with strategies to prevent and mitigate the effects of non-respiratory complications. [ABSTRACT FROM AUTHOR]
- Subjects :
- *AGE groups
*COVID-19
*OLDER people
*OLDER patients
*CHRONIC kidney failure
Subjects
Details
- Language :
- English
- ISSN :
- 10795006
- Volume :
- 75
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 145953101
- Full Text :
- https://doi.org/10.1093/gerona/glaa146