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SARS-CoV-2: Cytokine Storm and Therapy.

Authors :
Sajid, Mir Ibrahim
Tariq, Javeria
Awais, Shehar Bano
Naseem, Zehra
Balouch, Samira Shabbir
Abaidullah, Sajid
Source :
Annals of King Edward Medical University. 2020 Special Issue, Vol. 26, p243-251. 9p.
Publication Year :
2020

Abstract

SARS-CoV-2 can vary on a spectrum of an asymptomatic disease process, to a severe stage characterized by a "Cytokine Storm". This phenomenon is a pro-inflammatory state marked by an intricate interplay of a cocktail of chemokines and cytokines. An excessively raised serum levels of cytokines and chemokines can lead to the development of acute respiratory distress syndrome. This article highlights the pathophysiologic mechanisms responsible for creating this cytokine havoc and delves into potential therapeutic interventions. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20797192
Volume :
26
Database :
Academic Search Index
Journal :
Annals of King Edward Medical University
Publication Type :
Academic Journal
Accession number :
146335298