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Development and Validation of a Method for the "Dissolution" Test for Tablets of the New Bisphosphonate Sodium Prodronate.
- Source :
-
Pharmaceutical Chemistry Journal . Oct2020, Vol. 54 Issue 7, p772-775. 4p. - Publication Year :
- 2020
-
Abstract
- A method for the "Dissolution" test was developed and validated for tablets of the new bisphosphonate sodium prodronate and was compliant with the general normative requirements. Dissolution was carried out on an instrument with paddles rotating at a rate of 50 rpm. The quantity of drug entering solution over 45 min was assed by UV spectrophotometry via formation of complexes with copper ions, with an absorption peak at 237 nm. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SODIUM compounds
*COMPLEX ions
*COPPER compounds
*COPPER ions
Subjects
Details
- Language :
- English
- ISSN :
- 0091150X
- Volume :
- 54
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Pharmaceutical Chemistry Journal
- Publication Type :
- Academic Journal
- Accession number :
- 146734258
- Full Text :
- https://doi.org/10.1007/s11094-020-02269-w