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Kidney damage in COVID-19 patients with or without chronic kidney disease: Analysis of clinical characteristics and related risk factors.
- Source :
-
Indian Journal of Experimental Biology . Nov2020, Vol. 58 Issue 11, p811-817. 7p. - Publication Year :
- 2020
-
Abstract
- COVID-19 poses more risk to patients who already suffer from other diseases, particularly respiratory disorder. In this study, we analyzed the clinical characteristics and related risk factors during hospitalization of COVID-19 patients admitted with kidney damage. A total of 102 COVID-19 patients with kidney damage [irrespective of their chronic kidney disease (CKD) history] during hospitalization were included in this study. The patients were divided into a core group and a group who developed critical illness or death. Clinical data included age, gender, length of hospitalization, clinical manifestations, medical history, hypersensitive C-reactive protein (hs -CRP), high serum creatinine, low cardiac troponin I (cTnI), and hemoglobin. Univariate and multivariate logistic regression models were used to analyze the risk factors of patients' outcome. Among the outcomes, 75 patients (73.53%) were cured, 27 (26.47%) developed to critical illness or death, 20 (19.61%) of them died. A total of 36 (4.26%) out of 845 COVID-19 patients, developed acute kidney injury (AKI). Decreased oxygen saturation, elevated hs-CRP, elevated serum creatinine, elevated cTnI, and anemia were related factors for COVID-19 patients who developed to critical illness or death (P <0.05). Decreased oxygen saturation, elevated hs-CRP and anemia were not independent factors, but elevated serum creatinine and elevated cTnI were independent factors for COVID-19 patients who developed to critical illness or death (P <0.05). Among COVID-19 patients with or without CKD but with kidney damage during hospitalization, patients with elevated serum creatinine and elevated TnI, more likely to developed critical illness or death. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00195189
- Volume :
- 58
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Indian Journal of Experimental Biology
- Publication Type :
- Academic Journal
- Accession number :
- 146861278