Phytochemical composition and biological activity of Neurada procumbens L. growing in southern Algeria.

Neurada procumbens L. (Neuradaceae) is one of the most popular plants in the province of El-Oued in south-eastern Algeria. This study aimed to determine the antioxidant effectiveness of the 80% methanol extract of the aerial parts of the plant via the study of three-way antioxidant activity namely, 2,2′-azino-bis(3-ethylbenzothiazoline- 6-sulfonic acid) (ABTS), Catalase activity (CAT), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity assays in addition to examining its inhibitory capacity on the proliferation of hepatic (HepG2) and colon cancer (HCT116) cells. Chemical profiling of the major constituents of its extract was tentatively done using LC-MS in addition to quantitative determination of phenols, flavonoids, and chemical mineral elements by Inductively coupled plasma-optical emission spectrometry technique (ICP-OES). [ABSTRACT FROM AUTHOR]