Back to Search
Start Over
Ultrastable radical-doped coordination compounds with antimicrobial activity against antibiotic-resistant bacteria.
- Source :
-
Chemical Communications . 11/28/2020, Vol. 56 Issue 92, p14353-14356. 4p. - Publication Year :
- 2020
-
Abstract
- In the present work, we have introduced a series of stable radical-doped coordination compounds composed of donor–acceptor structures and shown to produce organic radicals in situ as a result of unconventional lone pair–π interactions in ambient conditions. Inconspicuous lone pair–π and C–H⋯π interactions were shown to play a key role in self-assembly as well as the charge transfer process, resulting in a long-lived charge-separated state able to generate organic radicals. The resultant species displayed broad-spectrum antimicrobial activity, including against multi-drug-resistant bacteria. This study unveiled the promise of reactive organic radical-doped materials as a new platform for developing antimicrobial agents that can overcome antibiotic resistance. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 56
- Issue :
- 92
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 147158474
- Full Text :
- https://doi.org/10.1039/d0cc06379g