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Insemination with isolated and virologically tested spermatozoa is a safe way for human immunodeficiency type 1 virus–Serodiscordant couples with an infected male partner to have a child
- Source :
-
Fertility & Sterility . Oct2004, Vol. 82 Issue 4, p857-862. 6p. - Publication Year :
- 2004
-
Abstract
- To enable serodiscordant couples to reproduce while minimizing the risk of infecting the female partner and to demonstrate the feasibility of including these couples in an insemination program.Prospective follow-up study.Ambulatory IUIs.Fifty-six HIV-1–serodiscordant couples with a male infected partner.Sperm cell separation by the gradient density method followed by the swim-up method, virological detection, and IUI after ovarian stimulation.Pregnancy rate, HIV-1 test, and p24 antigenemia in women.Two hundred thirteen IUIs were performed, and 37 pregnancies occurred, resulting in 33 births and 2 ongoing pregnancies. Fifty percent of couples have a child. No women were infected.Our study demonstrates the efficiency of an IUI program with prepared and virologically tested spermatozoa in serodiscordant couples with an HIV-1–infected male partner, allowing the couples to have children without transmission of the virus to the female partner. [Copyright &y& Elsevier]
- Subjects :
- *BUSINESS partnerships
*PREGNANCY
*FEASIBILITY studies
*RISK assessment
Subjects
Details
- Language :
- English
- ISSN :
- 00150282
- Volume :
- 82
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Fertility & Sterility
- Publication Type :
- Academic Journal
- Accession number :
- 14720367
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2004.02.128