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The Cyclohexa‐2,5‐dienyl Group as a Placeholder for Hydrogen: Organocatalytic Michael Addition of an Acetaldehyde Surrogate.
- Source :
-
Chemistry - A European Journal . 11/26/2020, Vol. 26 Issue 66, p15126-15129. 4p. - Publication Year :
- 2020
-
Abstract
- An aldehyde with a cyclohexa‐2,5‐dienyl group in the α‐position is introduced as a storable surrogate of highly reactive acetaldehyde. The cyclohexa‐2,5‐dienyl unit is compatible with an enantioselective Michael addition to nitroalkenes promoted by a Hayashi–Jørgensen catalyst and can be removed by a boron Lewis acid mediated C−C bond cleavage. The robust two‐step sequence does not require a large excess of the aldehyde component that is typically needed when directly using acetaldehyde. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LEWIS acids
*SCISSION (Chemistry)
*ACETALDEHYDE
*HYDROGEN
*NITROALKENES
*CATALYSTS
Subjects
Details
- Language :
- English
- ISSN :
- 09476539
- Volume :
- 26
- Issue :
- 66
- Database :
- Academic Search Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Academic Journal
- Accession number :
- 147223665
- Full Text :
- https://doi.org/10.1002/chem.202003764