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Effects of work status changes and perceived stress onglycaemiccontrol in individuals with type 1 diabetes during COVID-19 lockdown in Italy.
- Source :
-
Diabetes Research & Clinical Practice . Dec2020, Vol. 170, pN.PAG-N.PAG. 1p. - Publication Year :
- 2020
-
Abstract
- <bold>Aims: </bold>To evaluate the effects of COVID-19 lockdown on blood glucose control in individuals with type 1 diabetes (T1D) and to explore determinants of glucose variability.<bold>Methods: </bold>Fifty T1D patients undergoing continuous/flash glucose monitoring were recruited. The study's primary outcome was the change of time in range (TIR) from before to lockdown period. Three time-point comparisons of TIR, mean glucose levels (MG), estimated (e)HbA1c, time above (TAR) and below range (TBR), moderate/severe hypoglycemic events between pre-lockdown, lockdown and post-lockdown period were also performed. Information on lockdown-associated perceived stress, changes of work status and physical activity were recorded.<bold>Results: </bold>TIR significantly decreased (75(63-84)% vs.69(50-76)%,p < 0.001) whereas MG (154 ± 15 mg/dl vs.165 ± 25 mg/dl, p = 0.027) and eHbA1c (7.3(6.6-7.8)%vs.7.5(6.7-8.2)%,p = 0.031) increased from pre- to lockdown period; overall glucose control significantly improved when restriction ended. Lockdown-associated work loss/suspension independently predicted impaired TIR after adjustment for potential confounders (StandardizedĪ²: -0.29; 95%CĪ: -18.7 to -2.25;p = 0.01). Greater TAR, TBR and hypoglycemic events were also reported during the lockdown.<bold>Conclusion: </bold>In T1D Italian individuals, blood glucose control significantly worsened during the COVID-19 lockdown; work instability and related issues represented the main determinant of impaired glucose variability in this population. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GLYCEMIC control
*TYPE 1 diabetes
*STAY-at-home orders
*COVID-19
*BLOOD sugar
Subjects
Details
- Language :
- English
- ISSN :
- 01688227
- Volume :
- 170
- Database :
- Academic Search Index
- Journal :
- Diabetes Research & Clinical Practice
- Publication Type :
- Academic Journal
- Accession number :
- 147521266
- Full Text :
- https://doi.org/10.1016/j.diabres.2020.108513