Occurrence and recurrence of hepatocellular carcinoma in patients with HCV genotype 1b related cirrhosis treated with Ledipasvir + Sofosbuvir ± Ribavirin.

The article focuses on occurrence and recurrence of hepatocellular carcinoma in patients with hepatitis C virus (HCV) genotype 1b related cirrhosis treated with Ledipasvir + Sofosbuvir ± Ribavirin. Topics include the direct antiviral agents therapy for HCV has been revolutionary with a sustained virologic response rate with favorable effects on improving liver function complications, and the impact of treatment on de novo or recurrent hepatocellular carcinoma development is still debated.