Back to Search
Start Over
Catalytic asymmetric formal [3+2] cycloaddition of isatogens with azlactones to construct indolin-3-one derivatives.
- Source :
-
Chemical Communications . 1/7/2021, Vol. 57 Issue 2, p239-242. 4p. - Publication Year :
- 2021
-
Abstract
- The chiral amide–guanidine-catalyzed asymmetric formal [3+2] cycloaddition of isatogens with azlactones is presented. This strategy provided a facile and feasible route to chiral indolin-3-one derivatives bearing two contiguous tetrasubstituted stereocenters in moderate to good yields with high diastereoselectivities and enantioselectivities. A possible working mode was proposed to elucidate the chiral control of the process. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RING formation (Chemistry)
*GUANIDINES
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 57
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 147965537
- Full Text :
- https://doi.org/10.1039/d0cc06418a