Non-coding RNAs regulating androgen receptor signaling pathways in prostate cancer.

• The importance of androgen receptors in prostate cancer. • Application of ncRNAs in the diagnosis and treatment of prostate cancer. • Relationship between ncRNAs and androgen receptor signaling pathways. Prostate cancer (PCa) is one of the most common malignancies for men worldwide, and abnormal activation of the androgen receptor (AR) signaling plays an important role in the progression of PCa. However, in the androgen deprivation therapy (ADT), AR signaling inevitably recovered, as a result, exploring novel regulating mechanisms is of great importance. Recently, non-coding RNAs (ncRNAs), including microRNAs, long non-coding RNAs, circular RNAs, could be involved in the progression of PCa, and participate in the regulatory network of AR signaling in a variety of ways. This will help to identify novel molecular mechanisms to promote the development of PCa and find new potential therapeutic targets. In this review, we provide a synopsis of the latest research relating to ncRNAs and associated AR signaling in PCa. [ABSTRACT FROM AUTHOR]