Research progress on endometriosis-related immune events.

Endometriosis is a benign gynecologic disorder prevalent in 10%-15% of women at the reproductive age worldwide. Characterized by the presence of ectopic endometrial cells and stroma in various locations outside the endometrium, it is responsible for symptoms, including chronic pelvic pain, dysmenorrhea and subfertility, which significantly degrade the quality of the life of women. The etiology and pathophysiology of endometriosis remains to be elucidated. Changes in hormone level, immunoreaction, cytokines and chemokines in patients with endometriosis have been reported, and the data suggest that these alterations contribute to the pathology and symptoms of the disease. Furthermore, the association between autoimmunity and endometriosis has received increasing attention. [ABSTRACT FROM AUTHOR]