Potential role of mycosterols in hyperlipidemia – A review.

• Sterol-enriched fungi extracts are potential sources of bio molecules. • Ergosterol and derivatives from fungal source have promising health beneficial effects in hyperlipidemia. • Hypocholesterolemic effect of ergosterol from edible mushrooms. • Application of the mycosterols for the development of functionalized food formulations. Cardiovascular diseases associated with obesity are alarmingly increasing in both developed and developing countries. Obesity is mainly ascribed to higher lipid accumulation in the body. There are several simple approaches to treat this condition like lifestyle modification, dietary intervention, physical activities, drug treatment etc. There are many drugs available in the market to treat hyperlipidemia condition, but those drugs have many fatal adverse effects on human health. In view of this, it is reasonable to suggest some preventive measures by functional food ingredients as human health has acclimatized to these since thousands of years. Phytosterols have been studied since decades for its hypocholesterolemic effect in human nutrition. Although the mycosterols from fungi are still under- exploited, ergosterol and derivatives from fungal source have promising health beneficial effects in obesity associated cardiovascular diseases. This review aims to summarise the investigations on mycosterol with respect to obesity in the last decade and also scope of future research on its application in functional food supplements. [ABSTRACT FROM AUTHOR]