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Organoid model: A new hope for pancreatic cancer treatment?

Authors :
Chen, Haidi
Zhuo, Qifeng
Ye, Zeng
Xu, Xiaowu
Ji, Shunrong
Source :
BBA - Reviews on Cancer. Jan2021, Vol. 1875 Issue 1, pN.PAG-N.PAG. 1p.
Publication Year :
2021

Abstract

Pancreatic cancer is a rapidly progressing disease with a poor prognosis. We still have many questions about the pathogenesis, early diagnosis and precise treatment of this disease. Organoids, a rapidly emerging technology, can simulate the characteristics of pancreatic tumors. Using the organoid model of pancreatic cancer, we can study and explore the characteristics of pancreatic cancer, thereby effectively guiding clinical practice and improving patient prognosis. This review introduces the development of organoids, comparisons of organoids with other preclinical models and the status of organoids in basic research and clinical applications for pancreatic cancer. Unlabelled Image [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0304419X
Volume :
1875
Issue :
1
Database :
Academic Search Index
Journal :
BBA - Reviews on Cancer
Publication Type :
Academic Journal
Accession number :
148185594
Full Text :
https://doi.org/10.1016/j.bbcan.2020.188466