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抗体药物偶联物治疗恶性肿瘤临床应用 专家共识(2020 版).

Authors :
徐兵河
马飞
Source :
Chinese Journal of Oncology. Jan2021, Vol. 43 Issue 1, p78-91. 14p.
Publication Year :
2021

Abstract

Antibody-drug conjugate (ADC) is a type of targeted biological agent which connect cytotoxic drug to monoclonal antibody by a connector head, which enables monoclonal antibody acted as a carrier to efficiently transport small molecular cytotoxic drugs to target tumor cells. It is very important for clinicians to have an in-depth understanding of the molecular characteristics and mechanism of ADC drugs, rationally choose the appropriate dose, course of treatment and manage adverse reactions according to the indications during the clinical application of ADC drugs, which may even affect the survival of patients. Therefore, the consensus aims to conduct a systematic overview of commercially available ADC drugs, provide effective recommendations and references for clinicians to better apply and manage ADC drugs. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
02533766
Volume :
43
Issue :
1
Database :
Academic Search Index
Journal :
Chinese Journal of Oncology
Publication Type :
Academic Journal
Accession number :
148192439
Full Text :
https://doi.org/10.3760/cma.j.cn112152-20201112-00981