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Ambulatory blood pressure and risk of new‐onset atrial fibrillation in treated hypertensive patients.

Ambulatory blood pressure and risk of new‐onset atrial fibrillation in treated hypertensive patients.

Authors :
Coccina, Francesca
Pierdomenico, Anna M.
Ianni, Umberto
De Rosa, Matteo
De Luca, Andrea
Pirro, Davide
Pizzicannella, Jacopo
Trubiani, Oriana
Cipollone, Francesco
Renda, Giulia
Pierdomenico, Sante D.
Source :
Journal of Clinical Hypertension. Jan2021, Vol. 23 Issue 1, p147-152. 6p.
Publication Year :
2021

Abstract

The aim of this study was to evaluate the influence of clinic and ambulatory blood pressure (BP) on the occurrence of new‐onset atrial fibrillation (AF) in treated hypertensive patients. We studied 2135 sequential treated hypertensive patients aged >40 years. During the follow‐up (mean 9.7 years, range 0.4–20 years), 116 events (new‐onset AF) occurred. In univariate analysis, clinic, daytime, nighttime, and 24‐h systolic BP were all significantly associated with increased risk of new‐onset AF, that is, hazard ratio (95% confidence interval) per 10 mm Hg increment 1.22 (1.11–1.35), 1.36 (1.21–1.53), 1.42 (1.29–1.57), and 1.42 (1.26–1.60), respectively. After adjustment for various covariates in multivariate analysis, clinic systolic BP was no longer associated with increased risk of new‐onset AF, whereas daytime, nighttime, and 24‐h systolic BP remained significantly associated with outcome, that is, hazard ratio (95% confidence interval) per 10 mm Hg increment 1.09 (0.97–1.23), 1.23 (1.10–1.39), 1.16 (1.03–1.31), and 1.22 (1.06–1.40), respectively. Daytime, nighttime, and 24‐h systolic BP are superior to clinic systolic BP in predicting new‐onset AF in treated hypertensive patients. Future studies are needed to evaluate whether a better control of ambulatory BP might be helpful in reducing the occurrence of new‐onset AF. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15246175
Volume :
23
Issue :
1
Database :
Academic Search Index
Journal :
Journal of Clinical Hypertension
Publication Type :
Academic Journal
Accession number :
148205202
Full Text :
https://doi.org/10.1111/jch.14112