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Ionizable lipid nanoparticles for in utero mRNA delivery.

Authors :
Riley, Rachel S.
Kashyap, Meghana V.
Billingsley, Margaret M.
White, Brandon
Alameh, Mohamad-Gabriel
Bose, Sourav K.
Zoltick, Philip W.
Hiaying Li
Rui Zhang
Cheng, Andrew Y.
Weissman, Drew
Peranteau, William H.
Mitchell, Michael J.
Source :
Science Advances. 1/13/2021, Vol. 7 Issue 3, p1-15. 15p.
Publication Year :
2021

Abstract

The article offers information about the ionizable lipid nanoparticles for in utero mRNA delivery. It mentions about the clinical advances that enable the prenatal diagnosis of genetic diseases that are candidates for gene and enzyme therapies such as messenger RNA (mRNA)–mediated protein replacement.

Details

Language :
English
ISSN :
23752548
Volume :
7
Issue :
3
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
148221783
Full Text :
https://doi.org/10.1126/sciadv.aba1028